Living Organisms
Cayman Chemical CefsulodInsodIum salt hydra 1g
A cephalosporin antibiotic; active against 45 isolates of P. aeruginosa (MIC90 = 3.1 UG/ml) and acts synergistically against P. aeruginosa isolates when combined with gentamicin, tobramycin, amikacin, or mezlocillin; binds to P. aeruginosa PBP1a, PBP1b, and PBP3 but not PBP2, PBP4, or PBP5; increases survival in mice infected with various P. aeruginosa strains (ED50s = 1.93-137 mg/kg for all)
Escherichia coli (Migula) Castellani and Chalmers Strain NIH RZ1032 (ATCC 39737) - Frozen Culture, Transformation Host
Escherichia coli (Migula) Castellani and Chalmers, strain NIH RZ1032, is supplied as a frozen bacterial culture for laboratory use. This strain is used as a transformation host and supports propagation of filamentous phage M13mp8; it can produce M13mp2 phage that contains uracil in the DNA. The product is intended for BSL-1 laboratory applications and microbiology or molecular biology workflows.
- Organism: Escherichia coli (Migula) Castellani and Chalmers
- Strain designation: NIH RZ1032
- Product format: Frozen culture
- Recommended medium: LB agar/broth (Miller)
- Incubation temperature: 37°C
- Biosafety level: BSL 1
- Typical applications: Transformation host; phage propagation
- Notes: Material deposited with a patent depository; mission collection item
Sigma Aldrich Fine Chemicals Biosciences Hirudin from leeches lyoph
Hirudin is a 7 kDa acidic protein containing 65 amino acid residues that has an isoelectric point of 3.5-4.0. It is not glycosylated and lacks tryptophan arginine and methionine residues. It is chemically stable between pH 2-12 and at temperatures up to 80C.
Cayman Chemical PemetrexedodIum salt hydra 5mg
An antifolate with anticancer activity; an inhibitor of thymidylate synthase and dihydrofolate reductase (Kis = 109 and 7 nM, respectively); has increased potency for thymidylate kinase when polyglutaminated (Ki = 1.3 nM); an inhibitor of glycinamide ribonucleotide formyltransferase (Kis = 9,300 and 65 nM for the non-glutaminated and polyglutaminated enzyme) and aminoimidazole carboxamide ribonucleotide formyltransferase (Kis = 3,600 and 265 nM for the non-glutaminated and polyglutaminated, respectively); inhibits proliferation of CCRF-CEM cells but not 5,10-dideazatetrahydrofolate-resistant CR15 cells (IC50s = 0.254 and 200 µM, respectively); reduces tumor growth in A549, H1299, and PC-9 NSCLC mouse xenograft models but not in models using the same cell lines overexpressing thymidylate kinase
Citrobacter freundii (ATCC BAA-3249) Frozen Drug-Resistant Strain 990954, BSL-2
Citrobacter freundii strain 990954 is a drug-resistant clinical isolate recovered from a human skin ulcer in Brazil (2013). Supplied as a frozen culture for research use, this strain supports antimicrobial resistance studies, drug development, molecular assay validation, and comparative genomics.
- Product format: Frozen.
- Strain designation: 990954.
- Genome sequenced strain: Yes.
- Isolation source: Skin ulcer (human).
- Geographical isolation: Brazil.
- Applications: Antimicrobial resistance research, bioinformatics, drug development, assay validation.
- Storage conditions: -80°C or colder.
- Biosafety level: BSL 2.
- Suggested medium: Trypticase soy agar/broth.
- Incubation temperature: 37°C.
- Atmosphere: Aerobic.
- Gram stain: Negative.
- Packaging size: Not specified on manufacturer page.
- Concentration: Not specified on manufacturer page.
Cayman Chemical ClodronatSodIM salt hydra 10mg
A non-nitrogenous bisphosphonate that inhibits hydroxyapatite crystal growth (IC50 = 1.34 µM) and bone resorption; is cytotoxic to both osteoclasts and macrophages and has been used in biological research to selectively induce apoptosis of macrophage-like cells and cancer cells
Cayman Chemical DoxapramhydroCLOrID hydra 25mg
A central respiratory stimulant; increases respiration and phrenic nerve activity in anesthetized cats at a dose of 1.0 mg/kg; acts through carotid chemoreceptors, lacking activity in anesthetized cats following carotid denervation
Cayman Chemical L-TyrosInsodIum salt hydra 50g
A conditionally essential amino acid; a precursor in the biosynthesis of catecholamine neurotransmitters, melanins, and thyroid hormones; plasma, skeletal muscle, and erythrocyte levels are decreased in patients with chronic kidney disease